Artvigil Side Effects & Precautions Artvigil is considered very well tolerated in healthy individuals. As Artvigil is essentially one-half of Modafinil’s ingredients, similar safety precautions are warnings are observed. Artvigil has been prescribed for over 8 years, with zero recorded deaths to date. Side effects with Artvigil are minimal and infrequent. However, as with all drugs the following warnings and precautions should be read. Please read the official product insert of Nuvigil branded Armodafinil: CONTRAINDICATIONS NUVIGIL is contraindicated in patients with known hypersensitivity to modafinil or armodafinil. WARNINGS AND PRECAUTIONS Serious Rash, including Stevens-Johnson Syndrome: discontinue NUVIGIL at the first sign of rash, unless the rash is clearly not drug-related. Angioedema and Anaphylaxis Reactions: if suspected, discontinue NUVIGIL. Multi-organ Hypersensitivity Reactions: if suspected, discontinue NUVIGIL. Persistent Sleepiness: assess patients frequently for degree of sleepiness and, if appropriate, advise patients to avoid driving or engaging in any other potentially dangerous activity. Psychiatric Symptoms: use particular caution in treating patients with a history of psychosis, depression, or mania. Consider discontinuing NUVIGIL if psychiatric symptoms develop. Known Cardiovascular Disease: consider increased monitoring. ADVERSE REACTIONS Most common adverse reactions (≥5%): headache, nausea, dizziness, and insomnia. DRUG INTERACTIONS Steroidal contraceptives (e.g., ethynyl estradiol): use alternative or concomitant methods of contraception while taking NUVIGIL and for one month after discontinuation of NUVIGIL treatment. Cyclosporine: blood concentrations of cyclosporine may be reduced. CYP2C19 substrates, such as omeprazole, phenytoin, and diazepam: exposure of these medications may be increased. USE IN SPECIFIC POPULATIONS Pregnancy: based on animal data, may cause fetal harm.
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